The attacker, who was coming in as one of the foreign-based players in the side picked up the injury in training.
Hagan's absence is a big blow to Black Queen's coach Bashiru Hayford who lost another striker, Sandra Owusu Ansah through injury.
Coach Bashiru Hayford is yet to name his final 21 man squad for the competition which begin on November 17th.
Meanwhile, the Black Queens will play the Banyana Banyana of South Africa in a friendly on Sunday at the renovated Accra Sports Stadium.
The team lost to Zambia 3-2 and draw with Kenya 1-1 in their two international warm-up games.
Ghana is in group A with Algeria, Cameroon and Mali.
Source: GHANAsoccernet.com